Biological and Soft Mechanics Lab (BSML)
Biological and Soft Mechanics Lab (BSML)
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Article-Journal
Coordinated regulation of diverse F-actin organizations orchestrates F-actin pulses in the actomyosin network
Coordinated F-actin regulation drives actomyosin pulses in morphogenesis and cell migration.
Hao Li
,
Bing Liu
,
Jiaying Liu
,
Thomas Mangeat
,
Karine Belguise
,
Shi-Lei Xue
,
Xiaobo Wang
PDF
DOI
Necking of epithelial tissues with cellular topological transition
Cellular topological transitions govern epithelial tissue necking.
Yuan He
,
Shi-Lei Xue
PDF
DOI
Goblet cells mechanically breach the epithelial barrier in gut homeostasis
Goblet cells breach the epithelial barrier in response to mechanical forces, a process critical for gut homeostasis and immune defense.
Justine Creff
,
Yuan He
,
Sandra Bernat-Fabre
,
Etienne Buscail
,
Salomé Neuvendel
,
Vishnu Krishnakumar
,
Dhriti Saumya
,
Laurent Malaquin
,
Thomas Mangeat
,
Shi-Lei Xue
,
Denis Krndija
PDF
DOI
Mechanochemical bistability as a principle of robust morphogenesis
Mechanochemical bistability and tissue-scale coordination support robust morphogenesis.
Shi-Lei Xue
PDF
DOI
Mechano-sensitive feedback leads to morphological bistability in intestinal organoids
Mechano-sensitive feedback generates robust, timing-dependent morphogenesis in intestinal organoids.
Shi-Lei Xue
,
Edouard Hannezo
PDF
DOI
Differential tissue deformability underlies fluid pressure-driven shape divergence of the avian embryonic brain and spinal cord
Tissue deformability plays a key role in the fluid pressure-driven divergence of shape in the developing avian brain and spinal cord.
Susannah BP McLaren
,
Shi-Lei Xue
,
Siyuan Ding
,
Alexander K Winkel
,
Oscar Baldwin
,
Shreya Dwarakacherla
,
Kristian Franze
,
Edouard Hannezo
,
Fengzhu Xiong
PDF
Mechanochemical bistability of intestinal organoids enables robust morphogenesis
Mechanochemical bistability plays a key role in morphogenesis, with implications for tissue engineering and regenerative medicine.
Shi-Lei Xue
,
Qiutan Yang
,
Prisca Liberali
,
Edouard Hannezo
PDF
Tissue stresses caused by invasive tumour: a biomechanical model
This study explores tissue stresses induced by invasive tumors and presents a biomechanical model for understanding tumor-host interactions.
Shi-Lei Xue
PDF
Cell fate coordinates mechano-osmotic forces in intestinal crypt formation
Mechano-osmotic forces play a critical role in coordinating cell fate decisions during intestinal crypt formation, with implications for tissue development and regeneration.
Qiutan Yang
,
Shi-Lei Xue
,
Chii Jou Chan
,
Markus Rempfler
,
Dario Vischi
,
Francisca Maurer-Gutierrez
,
Takashi Hiiragi
,
Edouard Hannezo
,
Prisca Liberali
PDF
Cell monolayers sense curvature by exploiting active mechanics and nuclear mechanoadaptation
Mechano-osmotic forces play a critical role in coordinating cell fate decisions during intestinal crypt formation, with implications for tissue development and regeneration.
Marine Luciano
,
Shi-Lei Xue
,
Winnok H. De Vos
,
Lorena Redondo-Morata
,
Mathieu Surin
,
Frank Lafont
,
Edouard Hannezo
,
Sylvain Gabriele
PDF
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